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Viewing: Blog Posts Tagged with: nicotine and tobacco research, Most Recent at Top [Help]
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1. A brief history of the e-cigarette

Electronic cigarettes are growing in popularity around the world. With the announcement of vape as our Word of the Year, we have put together a timeline of the history of e-cigarettes.

1963
Herbert A. Gilbert patents a non-tobacco cigarette that heats a nicotine solution and produced steam, but it is never manufactured.

1979
Dr. Norman Jacobson, one of the pioneers of the word “vaping,” develops the Favor cigarette, a way to inhale nicotine with no smoke.

2003
Chinese pharmacist Hon Lik first develops an electronic alternative to traditional cigarettes.

2004
The first e-cigarettes, a Chinese invention, comes from the Ruyan company.

2007
E-cigarettes enter the US market.

February 2012
Nicotine and Tobacco Research publishes a study, entitled “Electronic Cigarettes: Effective Nicotine Delivery After Acute Administration,” which explores nicotine intake with different electronic cigarette devices.

June 2013
The Medicines and Healthcare Products Regulatory Agency will regulate e-cigarettes as medicines from 2016 when new European tobacco laws come into force.

December 2013
Nicotine and Tobacco Research publishes a study, entitled “Secondhand Exposure to Vapors From Electronic Cigarettes.” It reveals that “using an e-cigarette in indoor environments may involuntarily expose non-users to nicotine, but not to toxic tobacco-specific combustion products.”

Different types of electronic cigarettes by TBEC Review. CC BY 2.0 via Flickr.
Different types of electronic cigarettes by TBEC Review. CC BY 2.0 via Flickr.

December 2013
World leading tobacco experts argue that a recently published World Health Organization (WHO)-commissioned review of evidence on e-cigarettes contains important errors, misinterpretations, and misrepresentations, putting policy-makers and the public in danger of foregoing the potential public health benefits of e-cigarettes.”

September 2013
The American Academy of Pediatrics (AAP) urges the US Food and Drug Administration (FDA) to “issue a rule to regulate all tobacco products, including cigars, little cigars, e-cigarettes and others.”

15 January 2014
The Chicago City Council voted to regulate electronic cigarettes the same as traditional cigarettes,  which “prohibits the use of e-cigarettes in public places, requires stores selling them to keep them behind the counter, and prohibits their sale to minors.”

26 January 2014
The UK bans e-cigarettes for people under 18.

February 2014
The European Parliament approves regulations on e-cigarettes. “Beginning in mid-2016, advertising for e-cigarettes would be banned in the 28 nations of the European Union, as it already is for ordinary tobacco products. E-cigarettes would also be required to carry graphic health warnings and must be childproof. The amount of nicotine would be limited to 20 milligrams per milliliter, similar to ordinary cigarettes.”

March 2014
Journal of Psychiatric Research reports on e-cigarette use within different age groups and finds that “a notable proportion of adolescents and young adults who never smoked cigarettes had ever-used e-cigarettes. E-cigarette use was not consistently associated with attempting to quit tobacco among young adults. Adults most often reported e-cigarettes as a substitute for tobacco, although not always to quit. Reviewed studies showed a somewhat different pattern of e-cigarette use among young people (new e-cigarette users who had never used tobacco) versus adults (former or current tobacco users).”

14 April 2014
A US congressional report surveys the marketing tactics of e-cigarette companies, which directs sales towards youth, and calls on the FDA to set regulations for e-cigarette marketing.

24 April 2014
The FDA proposes regulations on e-cigarettes, which gives them authority over e-cigarettes and expands its’ authority over tobacco products. The AAP still urges the FDA to protect young people from the effects of e-cigarettes.

April 2014
A proposal from the FDA requires  e-cigarettes to “undergo an agency review,” which would ban e-cigarette sales to minors and require e-cigarettes to have warning labels.

April 2014
The AAP releases a statement on the dangers of e-cigarette poisoning in children.

4 May 2014
The AAP surveyed a random sample of adults, and according to the research presented, “the vast majority of young adults who have used the devices believe they are less harmful than regular cigarettes…”

12 May 2014
Tobacco Control BMJ releases a study on e-cigarette use and individuals with mental health conditions.

May 2014
A study for Nicotine and Tobacco Research finds that the vapors from e-cigarettes contain “toxic and carcinogenic carbonyl compounds,” and the amount of formaldehyde in the vapors is similar to the amount reported in tobacco smoke.

2 June 2014
A study titled “Exposure to Electronic Cigarette Television Advertisements Among Youth and Young Adults”, found that “exposure of young people ages 12 to 17 to e-cigarette ads on TV increased 256% from 2011 to 2013. Young adult (ages 18 to 24) exposure increased 321% over the same period.”

25 June 2014
The White House alters the wording of the Food and Drug Administration (FDA) tobacco regulations, allowing the online sale of e-cigarettes.

26 June 2014
The British Medical Association (BMA) calls to ban e-cigarette use in public. Doctors and medical students decide that e-cigarettes may lead to nicotine addiction.

July 2014
The BBC bans the use of e-cigarettes in all its offices and studios.

August 2014
A study from Nicotine and Tobacco Research states that “there is a risk of thirdhand exposure to nicotine from e-cigarettes,” although the exposure levels differ depending on the brand of the devices used.

August 2014
A study from Nicotine and Tobacco Research states that “in 2013, over a quarter million never-smoking youth had used e-cigarettes. E-cigarette use was associated with increased intentions to smoke cigarettes.”

24 August 2014
The American Heart Association (AHA) calls on the FDA for more research on e-cigarettes, to apply the same regulations on e-cigarettes as tobacco and nicotine products, and to create new regulations to prevent access, sale, and marketing to youth.

26 August 2014
A World Health Organization (WHO) report states that e-cigarettes need regulation to “impede e-cigarette promotion to non-smokers and young people; minimize potential health risks to e-cigarette users and nonusers; prohibit unproven health claims about e-cigarettes; and protect existing tobacco control efforts from commercial and other vested interests of the tobacco industry.”

The WHO reports that “governments should ban the use of electronic cigarettes in public places and outlaw tactics to lure young users.”

4 September 2014
The New England Journal of Medicine’s findings state that “like conventional cigarettes, electronic cigarettes may function as a ‘gateway drug’ that can prime the brain to be more receptive to harder drugs.”

October 2014
A study for Nicotine and Tobacco Research states that “over 75% of US adults reported uncertainty or disapproval of the use of e-cigarettes in smoke-free areas. Current cigarette smokers, adults aware or have ever used e-cigarettes were more supportive to exempting e-cigarettes from smoking restrictions.”

Headline image credit: Vaping an electronic cigarette by Jon Williams. CC BY 2.0 via Flickr.

The post A brief history of the e-cigarette appeared first on OUPblog.

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2. Vaping and the data on e-cigarettes

Oxford Dictionaries has selected vape as Word of the Year 2014, so we asked several experts to comment on the growth of electronic cigarettes and the vaping phenomenon.

Vaping is the term for using an electronic cigarette (e-cigarette). Since e-cigarettes involve inhaling vapour rather than smoke, it is distinct from smoking. The vapour looks a somewhat like cigarette smoke but dissipates much more quickly and has very little odour since it mostly consist of water droplets.

E-cigarettes started to become popular around 2010 and it is estimated they are currently being used by more than 2 million people in the United Kingdom and more than 5 million in the United States. Their sale is banned in many countries, including Australia and Canada, although surveys show that use in these is widespread since they can easily be obtained via the Internet.

E-cigarettes are devices in which a battery-powered heating element vaporises an ‘e-liquid’ usually containing propylene glycol or glycerol, nicotine, and flavourings. They are designed to provide much of the experience of smoking but with much lower risk, less annoyance to bystanders, and usually much more cheaply. Because they do not involve burning of tobacco, the concentrations of toxins in the vapour are typically a tiny fraction of those in cigarette smoke. The precise risk from using them is not known, but based on the vapour constituents it would be expected to be between 1% and 5% that of smoking.

Data on e-cigarette use are not available for most countries. By far the most complete data come from England where the ‘Smoking Toolkit Study’ (STS) collects data on usage from nationally representative samples of adults every month enabling this to be tracked closely over time. This study was established to track ‘key performance indicators’ relating to smoking and smoking cessation and has been going since 2007. Action on Smoking and Health also conduct large national surveys of adults and young people each year. Large scale surveys are also being conducted in the United States and some other countries. The data show that most people use e-cigarettes in an effort to protect their health either by stopping smoking altogether or cutting down. Despite misleading claims by some anti- e-cigarette advocates, use by never-smokers and long-term ex-smokers is extremely rare in the UK and US at present, and in England its prevalence in never-smokers and long-term ex-smokers is similar to the use of ‘licensed nicotine products’ (LNPs) such as nicotine patches, gum, or lozenges.

E-cigarettes come in many different forms. In England, the most commonly used ones at present are known as ‘cigalikes’ because they look something like a cigarette and often have a tip that glows when the user takes a puff. Becoming more popular are devices that involve a refillable ‘tank’. There are also more sophisticated ‘mod’ systems which are highly customised. These are often the choice of aficionados.

Most e-cigarette users probably obtain less nicotine from these devices than people typically do from cigarettes, but experienced vapers using tank systems or mods can obtain at least as much nicotine from their devices as do smokers.

When used in a quit attempt, on average e-cigarettes seem to improve the chances of successful quitting by about 50%, similar to licensed nicotine products when used as directed. The main difference appears to be that these devices are much more popular, and they seem to be effective when people use them without any support from a health professional. Currently the evidence still indicates that use of the drug varenicline or a licensed nicotine product with specialist behavioural support provides the best chance of quitting for those smokers who are willing to use this support and where such support is available.

Electronic Cigarettes by George Hodan via PublicDomainPictures.net.
Electronic Cigarettes by George Hodan via PublicDomainPictures.net.

When used for cutting down, daily (but not non-daily) use of e-cigarettes seems to be associated with a modest reduction in cigarette consumption on average. Use of licensed nicotine products for cutting down has been found to be associated with an increased likelihood of later smoking cessation. This has not yet been demonstrated for e-cigarettes, although smokers who use e-cigarettes daily do try to quit smoking more often than those who are not ‘dual users’.

Despite claims from some anti- e-cigarette advocates, in England and the United States, e-cigarettes are currently not acting as a ‘gateway’ to smoking in adolescents or ‘renormalising’ smoking. Youth and adult smoking have continued to decline steadily as e-cigarette use has grown and in England adult smoking cessation rates are somewhat higher than they were before e-cigarettes started to become popular. E-cigarette use in indoor public areas has not led to any increase in smoking in these areas in the UK and compliance with smoke-free legislation remains extremely high.

Some e-cigarette advertising seeks to glamorise vaping and in some countries appears to blur the boundaries between smoking and vaping. This has led to concern that it might make vaping attractive to non-smokers and countries such as the UK have regulated to prevent this.

There is some controversy over vaping. A number of high-profile public health advocates have engaged in what appears to be a propaganda campaign against them, creating an impression in the public consciousness that they are more dangerous than they are and that they are undermining tobacco control efforts when the evidence does not support this. It is reasonable to be concerned about what may happen in the future with tobacco companies dominating the e-cigarette market and being incentivised to maximise tobacco sales, but much of the anti- e-cigarette propaganda appears to be motivated more by a puritanical ethic than a dispassionate assessment of the evidence. Maximising the public heath opportunity presented by e-cigarettes, while minimising the potential threat, requires collecting good data, using this information to construct an appropriate regulatory strategy, and monitoring the situation closely to adjust the strategy as required. England appears to be leading the way in this approach designed to encourage smokers to use e-cigarettes to stop smoking, while not undermining use of potentially more effective quitting methods, and preventing e-cigarettes becoming a gateway into smoking. The Smoking Toolkit Study, the ASH surveys, and other research will continue to provide essential information needed to inform this strategy.

The post Vaping and the data on e-cigarettes appeared first on OUPblog.

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